Date
Jan 26, 2026
Publications
VenusX: Unlocking Fine-Grained Functional Understanding of Proteins
Journal
ICLR, 2026.
Fast and Interpretable Protein Substructure Alignment via Optimal Transport
Date
Jan 26, 2026
Journal
ICLR 2026
Venus-MAXWELL: Efficient Learning of Protein-Mutation Stability Landscapes using Protein Language Models
Date
Sep 19, 2025
Journal
NeurIPS, 2025
STAGE: A compact and versatile TnpB-based genome editing toolkit for Streptomyces
Date
Aug 26, 2025
Journal
Proceedings of the National Academy of Sciences, 2025
From high-throughput evaluation to wet-lab studies: advancing mutation effect prediction with a retrieval-enhanced model
Date
Jul 15, 2025
Journal
ISMB/ECCB, 2025.
Harnessing protein language model for structure-based discovery of highly efficient and robust PET hydrolases
Date
Jul 5, 2025
Journal
Nature Communications, 2025
VenusFactory: An Integrated System for Protein Engineering with Data Retrieval and Language Model Fine-Tuning
Date
Jul 1, 2025
Journal
ACL Demo, 2025.
A Deep Retrieval-Enhanced Meta-Learning Framework for Enzyme Optimum pH Prediction
Date
Mar 24, 2025
Journal
J. Chem. Inf. Model, 2025,
VenusMutHub: A systematic evaluation of protein mutation effect predictors on small-scale experimental data
Date
Mar 14, 2025
Journal
Acta Pharmaceutica Sinica B, 2025
Entropy-driven zero-shot deep learning model selection for viral proteins
Date
Feb 28, 2025
Journal
Physical Review Research, 2025,
AI-enabled Alkaline-resistant Evolution of Protein to Apply in Mass Production
Date
Feb 19, 2025
Journal
Elife, 2025,
Immunogenicity Prediction with Dual Attention Enables Vaccine Target Selection
Date
Jan 23, 2025
Journal
ICLR, 2025.
PROTSOLM: Protein Solubility Prediction with Multi-modal Features
Date
Jan 10, 2025
Journal
IEEE BIBM, 2024.
Secondary Structure-Guided Novel Protein Sequence Generation with Latent Graph Diffusion
Date
Jan 10, 2025
Journal
IEEE BIBM, 2024.
Protein Representation Learning with Sequence Information Embedding: Does it Always Lead to a Better Performance?
Date
Jan 10, 2025
Journal
IEEE BIBM, 2024.
A conditional protein diffusion model generates artificial programmable endonuclease sequences with enhanced activity
Date
Sep 10, 2024
Journal
Cell Discovery, 2024
Simple, Efficient, and Scalable Structure-Aware Adapter Boosts Protein Language Models
Date
Aug 7, 2024
Journal
J. Chem. Inf. Model, 2024,
PETA: evaluating the impact of protein transfer learning with sub-word tokenization on downstream applications
Date
Aug 2, 2024
Journal
Journal of Cheminformatics, 16, 92 (2024).
Enhancing efficiency of protein language models with minimal wet-lab data through few-shot learning
Date
Jul 2, 2024
Journal
Nature Communications, 2024,
Enhancing efficiency of protein language models with minimal wet-lab data through few-shot learning
Date
Jul 2, 2024
Journal
Nature Communications, 2024
Protein Engineering with Lightweight Graph Denoising Neural Networks
Date
Apr 17, 2024
Journal
Journal of Chemical Information and Modeling, 2024
Mn2+-induced structural flexibility enhances the entire catalytic cycle and the cleavage of mismatches in prokaryotic argonaute proteins
Date
Mar 14, 2024
Journal
Chemical Science, 2024,
Direct Observation of the Mutual Coupling Effect in the Protein–Water–Glycerol Mixture by Combining Neutron Scattering and Selective Deuteration
Date
Jan 6, 2024
Journal
The Journal of Physical Chemistry B, 2024,
ScaffoldGVAE: scaffold generation and hopping of drug molecules via a variational autoencoder based on multi-view graph neural networks
Date
Oct 4, 2023
Journal
Journal of Cheminformatics, 2023,
LS-MolGen: Ligand-and-Structure Dual-Driven Deep Reinforcement Learning for Target-Specific Molecular Generation Improves Binding Affinity and Novelty
Date
Jun 21, 2023
Journal
J. Chem. Inf. Model, 2023,
Observation of structural switch in nascent SAM-VI riboswitch during transcription at single-nucleotide and single-molecule resolution
Date
Apr 22, 2023
Journal
Nature Communications, 2023,
The evolution of anionic nanoclusters at the electrode interface in water-in-salt electrolytes
Date
Mar 17, 2023
Journal
Phys. Chem. Chem. Phys., 2023,
Creatinase: Using Increased Entropy to Improve the Activity and Thermostability
Date
Mar 16, 2023
Journal
The Journal of Physical Chemistry B, 2023,
SESNet: sequence-structure feature-integrated deep learning method for data-efficient protein engineering
Date
Feb 3, 2023
Journal
Journal of Cheminformatics, 2023,
SAM-DTA: a sequence-agnostic model for drug–target binding affinity prediction
Date
Dec 21, 2022
Journal
Briefings in bioinformatics, 2023
Proteome-wide 3D structure prediction provides insights into the ancestral metabolism of ancient archaea and bacteria
Date
Dec 21, 2022
Journal
Nature Communications, 2022,
Entropy Driving the Mg2+-Induced Folding of TPP Riboswitch RNA
Date
Nov 15, 2022
Journal
The Journal of Physical Chemistry B, 2022,
Conduction Mechanism in Graphene Oxide Membranes with Varied Water Content: From Proton Hopping Dominant to Ion Diffusion Dominant
Date
Aug 22, 2022
Journal
ACS Nano, 2022,
Non-ergodicity of a globular protein extending beyond its functional timescale
Date
Aug 4, 2022
Journal
Chem. Sci. 13, 9668–9677 (2022)
Loosely-packed dynamical structures with partially-melted surface being the key for thermophilic argonaute proteins achieving high DNA-cleavage activity
Date
Jul 22, 2022
Journal
Nucleic Acids Research, 2022,
The ω3 scaling of the vibrational density of states in quasi-2D nanoconfined solidsNature
Date
Jun 25, 2022
Journal
Nature Communications, 2022
Many-body effect renders universal subdiffusion to water on different proteins
Date
Apr 5, 2022
Journal
Physical Review Research, 2022,
Universal dynamical onset in water at distinct material interfaces
Date
Mar 28, 2022
Journal
Chemical Science, 2022,
Enhancement of thermal stability of proteinase K by biocompatible cholinium-based ionic liquids
Date
Mar 3, 2022
Journal
Physical Chemistry Chemical Physics, 2022,
